:: Last Update ::
  01 ตุลาคม 2564

ฤดีกร วิวัฒนปฐพี

หมายเลขโทรศัพท์ ::  074-288915
อีเมล์ ::  ruedeekorn.w@psu.ac.th
โฮมเพจส่วนตัว ::  .



 
ประวัติการศึกษา ::
  - เภสัชศาสตรบัณฑิต(เกียรตินิยมอันดับ1), เภสัชศาสตร์, มหาวิทยาลัยสงขลานครินทร์, 2530
  - เภสัชศาสตรมหาบัณฑิต, เภสัชอุตสาหกรรม, จุฬาลงกรณ์มหาวิทยาลัย, 2532
  - Doctor of Philosophy, Pharmaceutics, The school of Pharmacy, University of London, 2542

งานวิจัยที่สนใจ ::
  - Formulation and Drug Delivery


สาขาที่เชี่ยวชาญ ::
  - Oral drug delivery systems, Formulation of Biopesticides, Polymeric drug delivery, Dendrimers


ผลงานวิชาการ ::

  บทความวิจัยตีพิมพ์ในวารสารวิชาการ ::
  1. Ganugula R, Arora M, Jaisamut P, Wiwattanapatapee R, Jørgensen HG, Venkatpurwar VP, et al.  Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic beta cells for effective management of type 1 diabetes mellitus..  British J Pharmacol , 174:  2074-84, 2017.
  2. Petchsomrit A, Ganugula R, Wiwattanapatapee R Investigations on curcumin’s ability to enhance anticancer drug sensitivity to cancer cells..  Thai J Pharm Sci , 41:  41-44, 2017.
  3. Sangsen S, Wiwattanawongsa K, Likhitwitayawuid K, Sritularak B, Wiwattanapatapee R Comparisons between a self-microemulsifying system and lipid nanoparticles of oxyresveratrol on the physicochemical properties and Caco-2 cell permeability.  Eur J Lipid Sci Technol , 119:  1600053(1-13), 2017.
  4. Petchsomrit A, Sermkaew N, Wiwattanapatapee R Alginate-based composite sponges as gastroretentive carriers for curcumin-loaded self-microemulsifying drug delivery systems.  Sci Pharm , 85(11):  85010011(1-16), 2017.
  5. Sookkasem A, Chatpun S, Yuenyongsawad S, Sangsen Y, Wiwattanapatapee R Colon targeting of self-emulsifying and solid dispersions of curcumin using pectin beads as a delivery vehicle.  Lat Am J Pharm , 36(12):  2482-93, 2017.
  6. Chumthong A, Wiwattanapatapee R, Viernstein H, Pengnoo A. • Kanjanamaneesathian M. Spray-dried Powder of Bacillus megaterium for Control of Rice Sheath Blight Disease: Formulation Protocol and Efficacy Testing in Laboratory and Greenhouse.  Cereal Res. Commun., 44(1):  131-140, 2016.
  7. Arpa Petchsomrit, Namfa Sermkaew, Ruedeekorn Wiwattanapatapee Hydroxypropylmethyl cellulose-based sponges loaded self-microemulsifying curcumin: Preparation, characterization, and in vivo oral absorption studies..  J. Appl. Polym. Sci. , 133:  42966, 2016.
  8. Sangsen Y, Wiwattanawongsa K, Likhitwitayawuid K, Sritularak B, Graidist P, Wiwattanapatapee R Influence of surfactants in self-microemulsifying formulations on enhancing oral bioavailability of oxyresveratrol: studies in Caco-2 cells and in vivo..  Int. J. Pharm., 498:  294-303, 2016.
  9. Jaisamut P, Wiwattanawongsa K, Sangsen Y, Wiwattanapatapee R Enhanced curcumin supersaturation in gastrointestinal fluids by polymeric precipitation inhibitors.  Lat Am J Pharm , 35(4):  797-804, 2016.
  10. Sangsen Y, Wiwattanawongsa K, Likhitwitayawuid K, Sritularak B Wiwattanapatapee R Modification of oral absorption of oxyresveratrol using lipid based nanoparticles.  Colloids and Surface B: Biointerfaces, 131:  182-190, 2015.
  11. Nattha Kerdsakundee, Sirima Mahattanadul, Ruedeekorn Wiwattanapatapee Development and evaluation of gastroretentive raft forming systems incorporating curcumin-Eudragit EPO solid dispersions for gastric ulcer treatment.  Eur. J. Pharm. Biopharm, 94:  513-520, 2015.
  12. Sookkasem A, Chatpun S, Yuenyongsawad S, Wiwattanapatapee R Alginate beads for colon specific delivery of self-emulsifying curcumin.  J. Drug Deliv. Sci. Tech, 29(8):  159-166, 2015.
  13. Plyduang T, Lomlim L, Yuenyongsawad S, Wiwattanapatapee R Carboxymethylcellulose-tetrahydrocurcumin conjugates for colon-specific delivery of a novel anti-cancer agent, 4-amino tetrahydrocurcumin.  Eur. J. Pharm. Biopharm., 88(2):  351-360, 2014.
  14. Sermkaew N, Ketjinda W, Boonme P, Padoongsombat N and Wiwattanapatapee R  Liquid and solid self-microemulsifying drug delivery systems for improving the oral bioavailability of andrographolide from a crude extract of Andrographis paniculata.  European J. Pharm. Sci., 50 (3-4):  459-466, 2013.
  15. Jutharat Khochchawech, Chutima Tantikitti, Ruedeekorn Wiwattanapatapee  Effects of forms of weaning diets on acceptability, survival rate and growth in early juvenile Asian seabass (Lates calcarifer, Bloch).  Thai Fisheries Gazette, 66:  29-39, 2013.
  16. Sermkaew N, Wiwattanawongsa K, Kedjinda W and Wiwattanapatapee R Development, characterization and permeability assessment based on Caco-2 monolayers of self-microemulsifying floating tablets of tetrahydrocurcumin .  AAPS PharmSciTech, 14 (1):  321-331, 2013.
  17. Wiwattanapatapee R, Chumthong A, Pengnoo A, and Kanjanamaneesathian M Preparation and evaluation of Bacillus megaterium-alginate microcapsules for control of rice sheath blight disease .  World J. Microbiol. Biotech., 29:  1487-1497, 2013.
  18. Sangsen Y, Likhitwitayawuid K, Sritularak B, Wiwattanawongsa K, Wiwattanapatapee R Novel Solid Lipid Nanoparticles for Oral Delivery of Oxyresveratrol: Effect of the Formulation Parameters on the Physicochemical Properties and in vitro Release.  International Journal of Medical, Pharaceutical Science and Engineering , 7 (12):  873-880, 2013.
  19. Petchsomrit A, Sermkaew N , Wiwattanapatapee R Effect of Alginate and Surfactant on Physical Properties of Oil Entrapped Alginate Bead Formulation of Curcumin.  International Journal of Medical, Pharmaceutical Science and Engineering , 7 (12):  479-483, 2013.
  20. Jaisamut P, Wiwattanawongsa K, Wiwattanapatapee R  Influence of Natural Gum on Curcumin Supersaturation in Gastrointestinal Fluids .  International Journal of Medical, Pharmaceutical Science and Engineering, 7 (12):  631-634, 2013.
  21. Sriraksa S, Sermkaew N, Setthacheewakul S and Wiwattanapatapee R Floating Alginate Beads as Carriers for Self-Emulsifying System Containing Tetrahydrocurcumin.  Adv. Mater. Res., 506:  517-520, 2012.
  22. Setthacheewakul S, Kedjinda W, Maneenuan D and Wiwattanapatapee R Controlled release of oral tetrahydrocurcumin from a novel self-emulsifying floating drug delivery system (SEFDDS) .  AAPS PharmSciTech., 12:  152-164, 2011.
  23. Setthacheewakul S, Mahattanadul S, Padoongsombat N, Pichayakorn W and Wiwattanapatapee R Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rat.  Eur. J. Pharm. Biopharm., 76:  475-485, 2010.
  24. M. Kanjanamaneesathian, A. Chumthong, A. Pengnoo and R. Wiwattanapatapee Bacillus megaterium suppresses major thai rice diseases.  Asian Journal of Food & Agro-Industry, 2 (August):  s154-s159, 2009.
  25. ณัฐวดี สมบัติเทพสุทธิ์ ฤดีกร วิวัฒนปฐพี สนั่น ศุภธีรสกุล และสุนทร พิพิธแสงจันทร์  การขับไล่และลดการวางไข่ของสารสกัดหยาบจากรากของหนอนตายหยาก โล่ติ๊น และน้ำมันเมล็ดสะเดาช้างที่มีต่อผีเสื้อหนอนใยผัก .  วารสารวิชาการเกษตร, 27(2):  170-183, 2009.
  26. Wiwattanapatapee R, Sae-Yun A, Petcharat J, Ovartlarnporn C , Itharat, A Development and Evaluation of Granule and Emulsifiable Concentrate Formulations containing Derris elliptica Extract for Crop Pest Control.  Journal of Agricultural and Food Chemistry , 57:  11234-11241, 2009.
  27. Treetharnmathurot B, Dieudonne L, Ferguson EL, Schmaljohann D, Duncan R, Wiwattanapatapee R Dextrin-trypsin and ST-HPMA-trypsin conjugates: Enzyme activity, autolysis and thermal stability.  Int. J. Pharm., 373:  68-76, 2009.
  28. Treetharnmathurot B, Ovartlarnporn C, Wungsintaweekul J, Duncan R and Wiwattanapatapee R Effect of PEG molecular weight and linking chemistry on the biological activity and thermal stability of PEGylated trypsin.  Int. J. Pharm., 357 (1-2):  252-259, 2008.
  29. Pureesatien O, Ovatlarnporn O, Itharat A, Wiwattanapatapee R Quantitative HPLC Determination and Stability of Pyrido[1,2a]azepine Alkaloid, Pesticidal Compound in the Extract of Stemona curtisii and Water Dispersible Granules.  Chromatographia, 67 (7-8):  551-557, 2008.
  30. Chumthong A, Kanjanamaneesathian M, Pengnoo A, Wiwattanapatapee R Water-soluble granules containing Bacillus megaterium for biological control of rice sheath blight: Formulation, bacterial viability and efficacy testing .  World J. Microbiol. Biotech., 24 (11):  2499-2507, 2008.
  31. Hnoomak, Pengnoo A, Wiwattanapatapee R and Kanjanamaneesathian M In vitro testing of Bacillus megaterium against soil-borne fungal pathogen.  Naresuan agricultural journal, 11 (Suppl.):  167-173, 2008.
  32. Kanjanamaneesathian M, Wiwattanapatapee R, Pengnoo A , Oungbho K and Chumthong A Efficacy of novel formulations of Bacillus megaterium in suppressing sheath blight of rice caused by Rhizoctonia salani.  Plant Pathology Journal, 6:  195-201, 2007.
  33. Wiwattanapatapee R, Chumthong A, Pengnoo A and Kanjanamaneesathian M Effervescent fast-disintegrating bacterial formulation for biological control of rice sheath blight .  J. Controlled Release, 119:  229-235, 2007.
  34. Pengnoo A, Wiwatanapatapee R, Chumthong A, Kanjanamaneesathian M Bacterial antagonist as seed treatment to control leaf blight disease of bambara groundnut (Vigna subterranea).  World J Microbiol. Biotech., 22:  9-14, 2006.
  35. Sae-Yun A, Ovatlarnporn A, Itharat A, Wiwattanapatapee R Extraction of rotenone from Derris elliptica and Derris malaccensis by pressurized liquid extraction compared with maceration.  J. Chromatography A, 1125(2):  172-176, 2006.
  36. Pengnoo A, Wiwatanapatapee R, Chumthong A, Rotniam W and Kanjanamaneesathian M Preliminary study on the effect of culture medium on the number and size of endospores of Bacillus megaterium.  Silpakorn University Science and Technology Journal, 5:  129-139, 2005.
  37. Wiwattanapatapee R, Pengnoo A, Kanjanamaneesathian M, Matchavanich, W, Nilratana, L and Jantharangsri Floating pellets containing bacterial antagonist for control sheath blight of rice: Formulation, viability and bacterial release studies.  J. Controlled Release, 95(3):  453-460, 2004.
  38. Wiwattanapatapee R, Lomlim L and Saramunee K Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid .  J. Controlled Release, 88:  1-9, 2003.
  39. Wiwattanapatapee R., Padoongsombat N., Choochom T., Tang S. and Chaimongkol A. Water flea Moina macrocopa as a novel biocarrier of norfloxacin in aquaculture .  J. Controlled Release, 83 (1):  23-28, 2002.
  40. Wiwattanapatapee R, Srichana T, Maneenuan D and Chaimongkol A Bioencapsulation of sulfamethoxazole and trimethoprim in a novel live drug carrier: water flea Moina macrocopa.  Thai J. Pharm. Sci., 25 (suppl):  15, 2001.
  41. Wiwattanapatapee R and Srichana T Development of sulphamethoxazole/trimethoprim floating pellets.  Songklanakarin J. Sci. Tech., 23(4):  593-598, 2001.
  42. Malik N, Wiwattanapatapee R, Klopsch R, Lorenz K, Frey H, Weener JW, Meijer EW, Paulus W and Duncan R Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled PAMAM dendrimers in vivo.  J. Control. Rel., 65:  133-148, 2000.
  43. R. Wiwattanapatapee and R. Duncan Polyamidoamine dendrimers as a novel oral drug delivery system: Synthesis and characterisation of dendrimer-ibuprofen conjugates.  Thai. J. Pharm. Sci. , 24 (suppl):  67, 2000.
  44. R. Wiwattanapatapee, B. Carreno-Gomez, N. Malik, R. Duncan Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: A potential oral delivery system.  Pharm. Res., 17(8):  991-998, 2000.
  45. Wiwattanapatapee R, Carreno-Gomez B, Malik N and Duncan R,  PAMAM dendrimers as a potential oral drug delivery system: uptake to the rat intestine in vitro.  J. Pharm. Pharmacol. , , 50 (suppl):  99, 1998.
  46. Wiwattanapatapee R, Paulus W and Duncan R,  Preliminary biological evaluation of polyaminodendrimers.  J. Pharm. Pharmacol. , 49 (suppl):  28 , 1997.
  47. Wiwattanapatapee, R, and Pinsuwan, S.  The Stability of Freeze Dried Aloe Vera Powdered With Various Diluent. .  Songklanakarin J. Sci. Technol,, 15(2):  159-166, 1993.
  บทความวิจัยเสนอในที่ประชุมวิชาการและมีการพิมพ์รวมเล่ม ::
  1. Sombattapsut N, Wiwattanapatapee R, Subhadhirasakul S and Pipithsangchan S. . Antioviposition effects of root extract from Stemona curtisii, Derris elliptica and seed kernel oil from Thiem (Azadirachta excelca) on Diamondback moth (Plutella xylostella) .  ประชุมวิชาการพืชสวนแห่งชาติ ครั้งที่ 7 .  -, Naresuan University, Thailand,  26-30 May, 2008
  2. Hnoomak J, Pengnoo A and Wiwattanapatapee R. Bacillus megaterium: A formulation to control fungal soilborne plant pathogen..  The 6th IMT-GT UNINET Conference.  152, Penang, Malaysia,  28-30 August, 2008
  3. Kanjanamaneesathian M, Wiwattanapatapee R, Pengnoo A and Chumthong A. Development of bacterial formulations for controlling sheath blight disease of rice.  the 9th International Congress of Plant Pathology .  J. Plant Pathology (suppl.) S 2.411, Torino Italy,  24-29 August, 2008
  4. Sae-Yun A, Wiwattanapatapee R, Petcharat J, Ovatlarnporn C, Itharat A. Formulation Development of Derris Emulsifiable Concentrate for Crop Pest Control. .  The 35rd International Symposium on Controlled Release of Bioactive Materials.  -, New York, USA,  12-16 July, 2008
  5. Wiwattanapatapee R, Pengnoo A, Chumthong A and Kanjanamaneesathian M,. Effective alginate formulations of B. megaterium for biocontrol of rice disease..  The Nanobiosaccharide Dissemination Conference.  -, University of Hyderabad, India,  18-19 September, 2008
  6. Wiwattanapatapee R, Chumthong A, Pengnoo A and Kanjanamaneesathian M. . Bacterial antagonist effervescent formulation for control of rice disease..  The 33rd International Symposium on Controlled Release of Bioactive Materials.  -, Vienna, Austria,  22-26 July, 2006
  7. R. Wiwattanapatapee, A. Pengnoo, A. Chumthong and M. Kanjanamaneesathian. Formulation of Bacterial Antagonist B. firmus for control leaf blight disease of Bambara groundnut (Vigna subteranea).  The Fourth International Conference on Biopesticides (Oral presentation).  39, Chiang Mai, Thailand,  13-18 February, 2005
  8. W. Rojanarat , R. Wiwattanapatapee, A. Pengnoo, K. Oungbho and M. Kanjanamaneesathian. Efficacy of Bacillus megaterium granules in suppressing rice sheath bligth disease caused by Rhizoctonia solani.  The Fourth International Conference on Biopesticides.  37, Chiang Mai Thailand,  13-18 February, 2005
  9. A. Chumthong, R. Wiwattanapatapee, A. Pengnoo, L, Nilaratana and M. Kanjanamaneesathian. Culture and production of Bacillus megaterium endospore, antagonist of Rhizoctonia solani, from cheap substrate.  The Fourth International Conference on Biopesticides.  88, Chiang Mai, Thailand,  13-18 February, 2005
  10. C. Ovatlarnporn, R. Wiwattanapatapee, A. Itharat and W. Sainui. Development of natural plant stemona collinsae as insecticidal product against crop pests.  The Fourth International Conference on Biopesticides .  61, Chiang Mai Thailand,  13-18 February, 2005
  11. A.Yun, C. Ovatrarnporn, A. Itharat and R. wiwattanapatapee. Extraction of rotenone from Derris malaccensis and Derris elliptica by accelerated solvent extractor compared with soaking method.  The Fourth International Conference on Biopesticides.  137, Chiang Mai Thailand,  13-18 February, 2005
  12. Duncan R, Malik N, Wiwattanapatapee R, Xyloyiannis M, Padilla de Jesús OL, Fréchet JMJ , Manunta M, Izzo L and Jones A. . Dendrimers as drugs and carriers: A unique pharmacokinetics ? .  The 4th International Dendrimer Symposium.  -, Michigan, USA,  18-21 May, 2005
  13. Chumthong A, Wiwattanapatapee R, Pengnoo A, Kanjanamaneesathian M. . Efficacy of granule formulations containing Bacillus megaterium in suppressing sheath blight of rice.  Pharma IndoChina IV.  -, Hochiminh city, Vietnam,  10-13 November, 2005
  14. R. Wiwattanapatapee, M. Kanjanamaneesathian, A. Pengnoo, K. Oungbho, W. Rojanarat and A. Chumthong. Efficacy of bacterial antagonist formulations in suppressing sheath blight of rice.  The 31st International Symposium on Controlled Release of Bioactive Materials.  -, Honolulu, Hawaii, USA (Oral presentation),  12-16 June, 2004
  15. Seib F P, Xyloyiannis M, Pattrick N, Malik N, Wiwattanapatapee R, and Duncan R. . INTRACELLULAR TRAFFICKING OF POLYMERIC NANOMEDICINES .  Science, Engineering and Technology for Britain.  27, London, UK,  15 March, 2004
  16. R. Wiwattanapatapee, A. Pengnoo, M. Kanjanamaneesathian, K. Sathanasaowapak, L. Nilratana and A. Jantharangsri . Bacterial antagonist floating pellets for control sheath blight of rice.  The 30th International Symposium on Controlled Release of Bioactive Materials.  -, Glasglow, UK (Oral Presentation),  19-23 July, 2003
  17. M.Xyloyiannis, N.Malik, R.Wiwattanapatapee, P.Seib, P.Diamanti, R.Duncan. Nanotechnology in action: Towards better cancer treatments.  Science, Engineering and Technology for Britain.  68, London, UK,  17 March, 2003
  18. R. Wiwattanapatapee, L. Lomlim and K. Saramunee. Development of dendrimer conjugates for colon targeting .  The 29th International Symposium on Controlled Release of Bioactive Materials.  -, Seoul, Korea,  20-25 July, 2002
  19. R. Wiwattanapatapee, S. Tang, N. Padoongsombat, T.Srichana and A. Chaimongkol. Bioencapsulation of the antibacterial drug norfloxacin in water flea Moina macrocopa.  The 28th International Symposium on Controlled Release of Bioactive Materials.  612, San Diego, California, USA (Oral presentation),  24-27 June, 2001
  20. Wiwattanapatapee R, Jee RD and Duncan R, . PAMAM dendrimers as a potential oral drug delivery system: dendrimers complexes with piroxicam.  The International Symposium on Controlled release of Bioactive Material, Boston (Oral presentation).  145-146, Boston, USA,  20-23 June, 1999
  21. Duncan R, Malik N, Wiwattanapatapee R, and Klopsch R. Hyperbranched polymers: Novel drug carriers for oral and systemic administration, .  The International Symposium on recent Advances in Drug Delivery Systems.  55-58, Salt Lake City, USA, ,  19-21 Febuary, 1999
  22. Wiwattanapatapee R and Duncan R. Dendrimers as a potential oral drug delivery system: dendrimers: uptake of PAMAM dendrimers to the rat intestine in vitro and formation of dendrimer complexes with piroxicam .  United Kingdom & Ireland Controlled Release Society Symposiums on: Polymer drug delivery to the new millenium.  5, Birmingham, UK,  5-7 January, 1999
  23. Wiwattanapatapee R, Carreno-Gomez B, Malik N and Duncan R, . PAMAM dendrimers as a potential oral drug delivery system.  The International Symposium on Polymer Therapeutics-From Laboratory to Clinical Practice.  38, London, UK,  7-9 January, 1998
  24. Malik N, Wiwattanapatapee R and Duncan R. Dendritic polymers: Relationship of structure with biological properties.  The 24th International Symposium on Controlled Release of Bioactive Materials.  527-528, Stockholm, Sweden,  . June, 1997
  ประเภทหนังสือและตำรา ::
  1. ฤดีกร วิวัฒนปฐพี 2004, ระบบนำส่งยาทางปาก (Oral Drug Delivery Systems) ,  คณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ จำนวนหน้า 95
  2. ฤดีกร วิวัฒนปฐพี 1996, สารชะลอความแก่ในตำรับเครื่องสำอาง ,  คณะเภสัชศาสตร์ มหาวิทยาลัยสงขลานครินทร์ จำนวนหน้า 134
  งานวิชาการประเภทอื่นๆ (เช่น สิ่งประดิษฐ์ สิทธิบัตร ฯลฯ) ::
  1. อนุสิทธิบัตร เรื่อง ผลิตภัณฑ์ชีวภัณฑ์ควบคุมโรคพืช วิธีการเตรียมและการใช้ชีวภัณฑ์ดังกล่าว เลขที่ 0803001456 ลงวันที่ 30/4/2553 , 2010.
  2. คำขอรับอนุสิทธิบัตร เรื่อง ชีวภัณฑ์แบคทีเรียที่มีสารแขวนตะกอนกลุ่มพอลิแซคคาไรด์เป็นส่วนประกอบ เลขที่ 1003000251 ลงวันที่ 1/6/2553 , 2010.
  3. คำขอรับสิทธิบัตร เรื่อง ระบบนำส่งยาเซลฟ์-นาโนอิมัลซิฟายด์ในรูปแบบของแข็งชนิดลอยได้ สูตรเตทตระไฮโดรเคอคูมินในรูปแบบเซลฟ์-นาโนอิมัลซิฟายด์ฯ เลขที่ 1001000194 ลงวันที่ 8/2/2553 , 2010.
  4. คำขอรับสิทธิบัตร เรื่อง สูตรเตทตระไฮโดรเคอคูมินในรูปแบบเซลฟ์-นาโนอิมัลซิฟายด์ชนิดของเหลวและผลิตภัณฑ์ที่ได้จากการเตรียมโดยใช้สูตรดังกล่าว เลขที่ 0901002337 ลงวันที่ 27/5/2552, 2009.
  5. คำขอรับสิทธิบัตร เรื่อง กรรมวิธีการเตรียมสูตรตำรับแบคทีเรียปฏิปักษ์รูปแบบแกรนูลสำหรับฉีดพ่นเพื่อควบคุมโรคพืช เลขที่ 0701001394 ลงวันที่ 27/3/2550, 2007.
  6. คำขอรับสิทธิบัตร เรื่อง กรรมวิธีการเตรียมสูตรตำรับแบคทีเรียปฏิปักษ์รูปแบบเม็ดฟู่ในการควบคุมโรคพืช เลขที่ 0701002092 ลงวันที่ 27/4/2550, 2007.